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Publications in World Literature


Concepts and Strategies in New Drug Development, by P.U. Nwangwu, Pharm.D., Ph.D., Praeger Publishers, New York (1983)


  • Nwangwu, P.U.,  Hocslaw, T.L., and Stohs, S.J. “A Rapid in vivo Technique for Preliminary Screening of Antiarrhythmic Agents in Mice.” Arch. Int. Pharmacodyn. Therap, 229,219 (1977)
  • Nwangwu, P.U., “The Antiarrhythmic Activities, Acute Toxicity Profile and Hemodynamic Properties of some New and Selected Quinidine Analogs.” Doctoral Dissertation, University of Nebraska Medical Center, Omaha, Nebraska (1979) University Microfilms International. Order No. 8010544
  • Nwangwu, P.U., Holsclaw, T.L., Rosenberg, H., Small, L.D., and Stohs, S.J. “The Antiarrhythmic Activities of 6’-Hydroxycinchonine, 6’-Benzyloxycinchonine and 6’-Allyloxycinchonine as Compared to Quinidine in Mice. J. Pharm. Pharmacol. 46, 301 (1979)
  • Hamilton, C.A., Nwangwu, P.U., Parkinson, S., Rapport, J., and Stohs, S.J. “Mitral Valve Prolapse Syndrome: A Six Month Follow Up Study of Propranolol Theraphy.” Nebraska Medical Journal 46, 301 (1979)
  • Small, L. D., Rosenberg, H., Nwangwu, P.U., Holcslaw, T.L., and Stohs, S.J. “Partial Synthesis of 6’-Hydroxycinchonine and Its Antiarrhythmic Activity in Mice.” J. Med. Chem. 22, 11014 (1979)
  • Nwangwu, P.U., “Current Concepts on the Uses and Side Effects of L-Tryptophan.” Fl. Pharm. J. 44, 10, 7 (1980)
  • Nwangwu, P.U., “The Uses of Parenteral Phenytoin in Piggybacks.” Fl. Pharm. J. 44, 10, 7 (1980)
  • Nwangwu, P.U., “The Clinical Toxicology of Quinidine.” Clinical Toxicology Consultant 2,4 (1980)
  • Nwangwu, P.U., Meresh, K., Holcslaw, T.L., Rosenberg,  H., Small, L.D., and Stohs, S.J. “A Comparative Study on the Antiarrhythmic Activity and Acute Toxicity Profile of Quinidine and Four New Analogs in Mice.” Toxicology, 16, 73 (1980)
  • Nwangwu, P.U., “A Therapeutic Profile on Dobutamine.” Fl. Pharm J. 44,6,11 (1980)
  • Nwangwu, P.U., Hamilton, C.A., and Stohs, S.J. “Use of Antiarrhythmics in Mitral Valve Prolapse Syndrome: Rationale and Mechanisms of Action.” Current Therapeutic Research, 29,126 (1981)

  • Battles, K., German, M.R., and Nwangwu, P.U., “Merieux rabies Vaccine (Human Diploid Cell Vaccine).” Fl. Pharm. J. 45, 2:8 (1981)
  • Ingram, N., German, M.R., and Nwangwu, P.U., “Use of Betamethasone and Dexamethasone to Prevent Neonatal RDS.” Fl. Pharm. J. 45 5:14 (1981)

  • Kumer, K. and Nwangwu, P.U., “Bruton’s Agammaglobulinemia: Etiology, Diagnosis and Clinical Management.” Current Therapeutic Research 29:335 (1981)
  • Kumer, K. and Nwangwu, P.U., “Clinical Toxicology of Warfarin from Commercial Rodenticides: Symptoms, Diagnoses and Management.” Clinical Toxicology Consultants 3,1:23 (1981)
  • Nwangwu, P.U., Stohs, S.J., Rosenberg, H., Small, L.D., and Holcslaw, T.L., “The Antiarrhythmic Activity of 6’-Benzoyloxycinchonine, A New Quinidine Derivative.” Current Therapeutic Research 29:416 (1981)
  • Kumer, K. and Nwangwu, P.U., “Parenteral Drug Abuse: Clinical Toxicology and Sequelae.” Clinical Toxicology Consultants 3:119 (1981)
  • Twiggs, L.C. and Nwangwu, P.U., “The Effects of Parenteral Nutrition on Tumor Response.” Amer. J. Intravenous Therap. And Clin. Nutrition. 9, 5:10 (1981)
  • Nwangwu, P.U., Holcslaw, T.L., Stohs, S.J., Rosenberg, H., Small, L.D., and Modrak, J. B., “Hemodynamic Properties of New Quinidine Analog Cupreidine (6’-Hydroxycinchonine).” J. Cardiovasc. Pharmacol. 4:124 (1982)
  • Kumer K. and Nwangwu, P.U., “Pharmacokinetic Consideration in Pediatric Digoxin Dosing.” Current Therapeutic Research
  • Twiggs, L.C. and Nwangwu, P.U., “Perspectives on the Peripheral Use of Fructose Containing Hypertonic Solutions in Nutritional Support.” Amer. J. Intravenous Therap. and Clin. Nutrition 9 No. 2:9 (1982)
  • Nwangwu, P.U., “The Pharmacodynamics of Inflammation and Perspectives on Use of Steroids.” Current Therapeutic Research 30:253 (1981)
  • Roberts, G. and Nwangwu, P.U., “The Patient’s Right to Non-compliance.” Contemporary Pharmacy Practice, 5, 3:204 (1982)
  • Kumer, K., Nwangwu, J.T., and Nwangwu, P.U., “Perspectives on Digoxin Absorption from Small Bowel Resections.” Drug Intelligence and Clinical Pharmacy 17-121 (1983)
  • Clark, L.C. and Nwangwu, P.U., “Legal Aspects of Clinical Pharmacy Practice.”  Contemporary Pharmacy Practice 5, 3:198 (1982)
  • Twiggs, L.C. and Nwangwu, P.U., “Clinical Management of the Digoxin-Quinidine Interaction.” Clinical Toxicology Consultant Vol. 6 (1985)
  • Weaver, A. and Nwangwu, P.U., “A Rapid Technique for Identification of Time of Myocardial Infarction Employing Tc-99 Pyrophosphate.” Current Therapeutic Research, 30:122 (1981)
  • McGuire, L., Clyne, K.E., and Nwangwu, P.U., “Perspectives on Hetastarch, A New Plasma Expander.” Fl. Pharm. J. 46, 1:7 (1982)
  • Nwangwu, J.T., Clark, J.E., and Nwangwu, P.U., “Adverse Effects of Cigarette Smoking on the Pharmacological Actions of Some Drugs.” Clinical Toxicology Consultants 4:80 (1982)
  • Nwangwu, P.U., Stohs, S.J., Rosenberg, H., and Small, L.D., “Effects of Functional Group Substitutions at the 6’-Position on the Antiarrhythmic Activity of Quinidine.” Current Therapeutic Research 30:479 (1981)
  • Mangione, R.A. and Nwangwu, P.U., “Food Poisoning, Diagnosis and Management.” Clinical Toxicology Consultant 4, 4:123 (1982)
  • Nwangwu, P.U., “The Process of New Drug Development: Current Deficiencies and Opportunities for Improvement.” In Concepts and Strategies in New Drug Development, Nwangwu, P.U. (Ed.) Praeger Publishers, New York (1983)
  • Radonic, L.P., Mangione, R.A., and Nwangwu, P.U., “Toxic Shock Syndrome: Clinical Manifestations and Management.” Clinical Toxicology Consultant 5:1-9 (1983)
  • Williams, V.G. and Nwangwu, P.U., “Systemic Lupus Erythematosis: Symptoms, diagnosis and Management.” Clinical Toxicology Consultant 6:10-20 (1985)

  • Williams, V.G., Vernado, G.C., and Nwangwu, P.U., “Perspectives of the Clinical Pharmacology of Benzodiazepines.” Drugs of Today Vol. 21, No. 1 (1985)

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